As a seasoned R&D scientist, Dr Alejandra Solache has pioneered the development and adoption of sustainable, consistent antibodies with the goal of addressing the reproducibility crisis in the life sciences industry. She has focused on identifying and removing variables in the antibody development process. At Abcam, she successfully implemented a move to large scale in-house production of recombinant reagents, delivering over 20,000 novel recombinant monoclonal antibodies to date. Critical to this, she established comprehensive validation programs to ensure specificity, sensitivity and overall performance, including the use of gold standard CRISPR gene-edited knockout (KO) cell lines that has created an industry-leading portfolio of over 3,000 KO validated antibodies.

Alejandra participates in many sector initiatives with academic and industry thought leaders and was the driving force behind Abcam’s first ‘Reproducible Science Week’ conference. She actively champions the need for researchers to fully validate their own reagents to further address the issue of poor experimental reproducibility.